Home Site Map Contact Us
  Back to Salix Products
XIFAXAN

Travel Tips

  • XIFAXAN Home
  • About XIFAXAN
  • Safety & Side Effects
  • What Is “Gut Flora?”
  • FAQs
  • Travelers’ Diarrhea
  • Patient Education Brochure
  • Travel Tips
  • Reimbursement Information

Prevent Travelers’ Diarrhea (TD)

This information is intended for U.S. residents only.

How can I avoid travelers’ diarrhea?

When you will be traveling to an area where the water may not be clean, see your doctor 4 to 6 weeks before your trip. Your doctor may want to give you some medicines, such as antibiotics or shots, to protect you from illness while you are away. During your trip, be careful about the following things:

  • Do not drink tap water and do not use it to brush your teeth
  • Do not drink bottled water if the seal on the bottle has been broken
  • Do not use ice unless you're sure it's made from purified water
  • Do not drink milk or eat dairy products that have not been pasteurized (heated to a temperature that kills all germs)
  • Do not eat raw fruits or vegetables unless they can be peeled and you are the one who peels them
  • Do not eat cut-up fruit salad
  • Do not eat lettuce or other leafy raw vegetables (such as spinach)
  • Do not eat raw or rare (slightly cooked) meat or fish
  • Do not eat food from people who sell it on the street

Risk areas for travelers’ diarrhea

Travelers’ Diarrhea Risk Areas

Click here to download the map (PDF 2.6MB)


Get Adobe Acrobat Reader

Get Acrobat Reader

SAFETY CONSIDERATIONS

Xifaxan® (rifaximin) Tablets are indicated for the treatment of patients (≥12 years of age) with travelers’ diarrhea caused by noninvasive strains of Escherichia coli. Xifaxan should not be used in patients with diarrhea complicated by fever or blood in the stool or diarrhea due to pathogens other than Escherichia coli. Xifaxan should be discontinued if diarrhea symptoms get worse or persist more than 24-48 hours and alternative antibiotic therapy should be considered. Escherichia coli has been shown to develop resistance to rifaximin in vitro. However, the clinical significance of such an effect has not been studied.

In clinical trials, Xifaxan was generally well tolerated. The most common side effects (vs. placebo) were flatulence 11.3% (vs. 19.7%), headache 9.7% (vs. 9.2%), abdominal pain 7.2% (vs. 10.1%), rectal tenesmus 7.2% (vs. 8.8%), defecation urgency 5.9% (vs. 9.2%) and nausea 5.3% (vs. 8.3%).

For complete Prescribing Information, please click here.


For product information, adverse event reports, and product complaint reports please call:

Salix Product Information Call Center
Phone: 1-800-508-0024
Fax: 1-510-595-8183
Email:

  • Travelers' Diarrhea Fact Pack

  • XIFAXAN Physician Resource Center

  • XIFAXAN Product Prescribing Information

Click here for Patient Brochure.