About MoviPrep
This information is intended for U.S. residents only.
Indication
MoviPrep® is indicated for cleansing of the colon as a preparation for colonoscopy in adults 18 years of age or older.
Product Summary
FDA approved in August 2006, MoviPrep provides the efficacy of a 4-L PEG lavage in a tolerable lower volume. MoviPrep has demonstrated excellent or good colon cleansing in approximately 9 out of 10
patients1, and is the only PEG lavage with ascorbic acid and sodium ascorbate to both enhance taste and increase stool volume by 27%, thereby eliminating the need for concomitant
prokinetic agents.2 Because MoviPrep offers a tolerable dosing regimen that does not require the use of bisacodyl tablets, patients avoid bisacodyl-associated abdominal cramping.
Additionally, MoviPrep provides flexible dosing with a convenient evening start-time so that patients do not need to miss work the day prior to the procedure.
The MoviPrep regimen helps to promote adequate hydration with an additional 1L of clear liquid of the patient's choice to be taken during the bowel preparation process. Adequate hydration can help improve
patients' recovery time post-procedure. MoviPrep has an excellent safety profile, with less vomiting, nausea, and abdominal pain than 4L PEG lavage and no serious adverse events reported in clinical trials.
1,2
For patients' convenience, MoviPrep comes with an easy-to-handle, pre-marked 1-L bottle for reconstitution and simple dosing instructions.
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Dosing
2 liters of MoviPrep solution, dosed in 8 oz. increments every 15 minutes until the graduated 1L container is empty on the evening before the scheduled procedure. The second liter of MoviPrep solution may be
taken either an hour and a half after the end of the first liter during the same evening, or it may be taken the following morning and finished at least 1 hour before the scheduled procedure. Patients should also
drink an additional liter of any clear liquid of their choice (except for red or purple colored drinks) during the course of the bowel prep regimen to help ensure adequate hydration. Please check with your doctor
if you have any questions about dosing.
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References
MoviPrep® (PEG-3350, sodium sulfate, sodium chloride, potassium chloride, sodium ascorbate and ascorbic acid for oral solution) is indicated for cleansing of the
colon as a preparation for colonoscopy in adults 18 years of age or older. MoviPrep is contraindicated in patients who have had a severe hypersensitivity reaction
to any of its components. MoviPrep should be used with caution in patients using concomitant medications that increase the risk of electrolyte abnormalities, in patients with known or suspected hyponatremia,
severe ulcerative colitis, ileus, gastrointestinal obstruction or perforation, gastric retention, toxic colitis, toxic megacolon, or glucose-6-phosphate dehydrogenase deficiency. In clinical trials, abdominal
distention, anal discomfort, thirst, nausea, and abdominal pain were the most common adverse reactions to MoviPrep administration. MoviPrep contains a maximum of 2.33 mg of phenylalanine per treatment.
Consult with your physician to see if this product is right for you.
For complete Prescribing Information, please click here.
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